Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570661 | 0.87 | — | — | |
| SCHEMBL570081 | 0.84 | NOTUM (0.37) | NPFFR2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL872479 | 0.81 | CES2 (0.34) | — | |
| SCHEMBL14962354 | 0.81 | CES2 (0.34) | — | |
| SCHEMBL14955984 | 0.79 | NOTUM (0.32) | — | |
| SCHEMBL16689397 | 0.79 | — | — | |
| SCHEMBL19268219 | 0.79 | CES1 (0.38) | NPFFR2KDR | |
| SCHEMBL113435 | 0.77 | HPGD (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL981100 | 0.76 | NPFFR2 (0.50) | NPFFR2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL29738557 | 0.76 | TTR (0.48) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987464-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-03-24 | — | — | US | disclosed |
| US-20140135496-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-05-15 | — | — | US | disclosed |
| US-8673951-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| EP-1932836-B1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND HARMFUL ORGANISM-CONTROLLING AGENT | NISSAN CHEMICAL IND LTD (JP) | 2013-11-06 | — | — | EP | disclosed |
| US-20110144334-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-06-16 | — | — | US | disclosed |
| US-7951828-B1 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-05-31 | — | — | US | disclosed |
| EP-1932836-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND HARMFUL ORGANISM-CONTROLLING AGENT | Nissan Chemical Industries, Ltd. (JP) | 2008-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144334-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | OR10J3, OR51E2, ORMDL3 | NPFFR2 1409/4885HTR3E 2340/4885HTR3B 2263/4885 |
| US-20140135496-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | OR10J3, OR51E2, ODC1 | NPFFR2 1740/4885HTR3E 2032/4885HTR3B 1850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.