SCHEMBL17995247

SCHEMBL17995247

CNC(=N)NCCCC(N)C(C)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.41
OTC P00480 1/20 0.37
GNAI3 P08754 1/20 0.36
GNAO1 P09471 1/20 0.36
GNAI1 P63096 1/20 0.36
RRM1 P23921 1/20 0.35
KISS1R Q969F8 1/20 0.34
ANPEP P15144 2/20 0.33
RNPEP Q9H4A4 2/20 0.33
DNPEP Q9ULA0 1/20 0.33
DDAH1 O94760 1/20 0.33
NOS3 P29474 2/20 0.33
NOS1 P29475 2/20 0.33
NOS2 P35228 2/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
HIF1A Q16665 1/20 0.32
PAOX Q6QHF9 2/20 0.32
MEN1 O00255 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12279136 1.00 DPP7 (0.41) DPP7OTCGNAI3GNAO1GNAI1
Tilarginine SCHEMBL1321022 0.87 OTC (0.49) DPP7OTCDDAH1NOS3NOS1
Tilarginine SCHEMBL6370536 0.86 OTC (0.51) DPP7OTCDDAH1NOS3NOS1
SCHEMBL19608041 0.86 DPP7 (0.41) DPP7OTCGNAI3GNAO1GNAI1
Tilarginine SCHEMBL12028766 0.86 OTC (0.51) DPP7OTCDDAH1NOS3NOS1
Tilarginine SCHEMBL315843 0.86 OTC (0.51) DPP7OTCDDAH1NOS3NOS1
Tilarginine SCHEMBL2229626 0.85 OTC (0.50) DPP7OTCDDAH1NOS3NOS1
SCHEMBL18542868 0.84 DPP7 (0.44) DPP7OTCGNAI3GNAO1GNAI1
SCHEMBL18542869 0.84 DPP7 (0.44) DPP7OTCGNAI3GNAO1GNAI1
SCHEMBL19368710 0.84 DPP7 (0.44) DPP7OTCGNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9890318-B1 Drilling fluid additive composition and water-based drilling fluid suitable for high-pressure plugging CHINA UNIVERSITY OF PETROLEUM (BEIJING) (CN) 2018-02-13 US disclosed
US-9834717-B1 Drilling fluid additive composition and pseudo oil-based drilling fluid suitable for horizontal shale gas wells CHINA UNIVERSITY OF PETROLEUM (BEIJING) (CN) 2017-12-05 US disclosed
US-20170335163-A1 DRILLING FLUID ADDITIVE COMPOSITION AND PSEUDO OIL-BASED DRILLING FLUID SUITABLE FOR HORIZONTAL SHALE GAS WELLS CHINA UNIVERSITY OF PETROLEUM (BEIJING) (CN) 2017-11-23 US disclosed
US-9790417-B1 High-density water-based drilling fluid suitable for horizontal shale gas wells CHINA UNIVERSITY OF PETROLEUM (BEIJING) (CN) 2017-10-17 US disclosed
US-9783726-B1 Environment-friendly water-based drilling fluid applicable to horizontal shale gas wells CHINA UNIVERSITY OF PETROLEUM (BEIJING) (CN) 2017-10-10 US disclosed
US-9783726-B1 Environment-friendly water-based drilling fluid applicable to horizontal shale gas wells CHINA UNIVERSITY OF PETROLEUM (BEIJING) (CN) 2017-10-10 US disclosed
US-9528041-B2 Bionic drilling fluid and preparation method thereof CHINA UNIVERSITY OF PETROLEUM (BEIJING) (CN) 2016-12-27 US disclosed
US-20160333248-A1 BIONIC DRILLING FLUID AND PREPARATION METHOD THEREOF CHINA UNIVERSITY OF PETROLEUM (BEIJING) (CN) 2016-11-17 US disclosed
US-20160230063-A1 BIONIC SHALE INHIBITOR AND PREPARATION METHOD THEREOF AND DRILLING FLUID CHINA UNIVERSITY OF PETROLEUM (BEIJING) (CN) 2016-08-11 US disclosed