Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17996902 | 0.92 | KDM4E (0.47) | KDM4EATML3MBTL1MAPTLMNA | |
| SCHEMBL17996903 | 0.89 | KDM4E (0.43) | KDM4EATML3MBTL1MAPTLMNA | |
| SCHEMBL17996904 | 0.89 | KDM4E (0.47) | KDM4EATML3MBTL1MAPTLMNA | |
| SCHEMBL17996910 | 0.86 | KDM4E (0.42) | KDM4EATML3MBTL1MAPTLMNA | |
| SCHEMBL21890204 | 0.86 | KDM4E (0.47) | KDM4EATML3MBTL1MAPTLMNA | |
| SCHEMBL21890337 | 0.86 | KDM4E (0.49) | KDM4EATML3MBTL1MAPTLMNA | |
| SCHEMBL16067003 | 0.85 | KDM4E (0.43) | KDM4EATML3MBTL1MAPTLMNA | |
| SCHEMBL20821408 | 0.84 | KDM4E (0.45) | KDM4EATML3MBTL1MAPTLMNA | |
| SCHEMBL17997065 | 0.84 | KDM4E (0.35) | KDM4EMAPTLMNATP53POLB | |
| SCHEMBL17997068 | 0.84 | KDM4E (0.42) | KDM4EATML3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016125110-A1 | BISIMIDAZOLODIAZOCINES | IDEMITSU KOSAN CO., LTD. (JP) | 2016-08-11 | — | — | WO | disclosed |