SCHEMBL21890337

SCHEMBL21890337

c1ccc(-n2c3ccccc3c3c4c5ccccc5c5nc6ccccc6n5c4ccc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.49
MAPT P10636 4/20 0.49
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.49
POLB P06746 1/20 0.49
HSD17B10 Q99714 1/20 0.49
HPGD P15428 6/20 0.48
ALDH1A1 P00352 5/20 0.48
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.43
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CASP1 P29466 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17996902 0.93 KDM4E (0.47) KDM4EMAPTLMNATP53POLB
SCHEMBL17996904 0.92 KDM4E (0.47) KDM4EMAPTLMNATP53POLB
SCHEMBL16067003 0.91 KDM4E (0.43) KDM4EMAPTLMNATP53POLB
SCHEMBL21890203 0.90 KDM4E (0.48) KDM4EMAPTLMNATP53POLB
SCHEMBL21890204 0.89 KDM4E (0.47) KDM4EMAPTLMNATP53POLB
SCHEMBL24290642 0.89 KDM4E (0.42) KDM4EMAPTLMNATP53POLB
SCHEMBL16066548 0.89 KDM4E (0.47) KDM4EMAPTLMNATP53POLB
SCHEMBL16066538 0.89 KDM4E (0.47) KDM4EMAPTLMNATP53POLB
SCHEMBL24290644 0.89 KDM4E (0.42) KDM4EMAPTLMNATP53POLB
SCHEMBL16066519 0.88 KDM4E (0.46) KDM4EMAPTLMNATP53POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230068759-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2023-03-02 US disclosed
US-20220073517-A1 BLUE THERMALLY ACTIVATED DELAYED FLUORESCENT EMITTERS AND HOSTS BASED ON FUNCTIONALIZED IMIDAZOLYL GROUPS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2022-03-10 US disclosed
US-20200227656-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2020-07-16 US disclosed
US-10615349-B2 Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220073517-A1 BLUE THERMALLY ACTIVATED DELAYED FLUORESCENT EMITTERS AND HOSTS BASED ON FUNCTIONALIZED IMIDAZOLYL GROUPS IK, ETFA, GDI1 KDM4E 3679/4885MAPT 690/4885LMNA 2844/4885
US-20200227656-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES SUN2, STAU1, HELZ KDM4E 4206/4885MAPT 2512/4885LMNA 2450/4885
US-20230068759-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES SUN2, STAU1, HELZ KDM4E 4206/4885MAPT 2512/4885LMNA 2450/4885
US-10615349-B2 Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues SUN2, STAU1, HELZ KDM4E 4206/4885MAPT 2512/4885LMNA 2450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.