Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 18/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17997437 | 0.93 | ECE1 (0.55) | ECE1 | |
| SCHEMBL926424 | 0.85 | PPARG (0.49) | ECE1 | |
| SCHEMBL926660 | 0.84 | MAOB (0.47) | ECE1 | |
| SCHEMBL926515 | 0.82 | PPARG (0.45) | ECE1 | |
| SCHEMBL926845 | 0.82 | ECE1 (0.53) | ECE1 | |
| SCHEMBL931800 | 0.78 | PPARG (0.59) | — | |
| SCHEMBL4655323 | 0.77 | ECE1 (0.63) | ECE1 | |
| SCHEMBL3805268 | 0.77 | ECE1 (0.57) | ECE1 | |
| SCHEMBL17997441 | 0.77 | ECE1 (0.50) | ECE1 | |
| SCHEMBL17997438 | 0.76 | ECE1 (0.55) | ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235015-B1 | AZABICYCLIC CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2016-08-24 | — | — | EP | claimed |
| EP-2235015-B1 | AZABICYCLIC CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2016-08-24 | — | — | EP | disclosed |