Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 7/20 | 0.51 |
| ▸ | BRAF | P15056 | 6/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 3/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3805268 | 0.93 | ECE1 (0.57) | ECE1BRAFEGFRRETABL1 | |
| SCHEMBL17997441 | 0.92 | ECE1 (0.50) | ECE1BRAFEGFRRETABL1 | |
| SCHEMBL17997436 | 0.91 | ECE1 (0.51) | ECE1BRAFEGFRRETABL1 | |
| SCHEMBL17997438 | 0.86 | ECE1 (0.55) | ECE1BRAFEGFRRETCDK8 | |
| SCHEMBL926797 | 0.85 | TNIK (0.51) | PIK3CAMTORCDK8 | |
| SCHEMBL17997440 | 0.83 | ECE1 (0.46) | ECE1BRAFEGFRRETABL1 | |
| SCHEMBL926044 | 0.82 | TNIK (0.49) | ECE1BRAFKITPIK3CAMTOR | |
| SCHEMBL940547 | 0.82 | ECE1 (0.49) | ECE1 | |
| SCHEMBL15300385 | 0.81 | ECE1 (0.45) | ECE1 | |
| SCHEMBL940148 | 0.80 | ECE1 (0.48) | ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235015-B1 | AZABICYCLIC CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2016-08-24 | — | — | EP | claimed |
| EP-2235015-B1 | AZABICYCLIC CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2016-08-24 | — | — | EP | disclosed |