Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28675328 | 0.98 | LMNA (0.43) | LMNASMN1; SMN2OPRM1FAAHALDH1A1 | |
| SCHEMBL30786802 | 0.94 | LMNA (0.46) | LMNASMN1; SMN2FAAHALDH1A1HSD17B10 | |
| SCHEMBL26999627 | 0.94 | LMNA (0.46) | LMNASMN1; SMN2FAAHALDH1A1HSD17B10 | |
| SCHEMBL31284732 | 0.94 | LMNA (0.46) | LMNASMN1; SMN2FAAHALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9803172 | 0.92 | LMNA (0.45) | LMNASMN1; SMN2FAAHALDH1A1HSD17B10 | |
| SCHEMBL29059516 | 0.92 | LMNA (0.45) | LMNASMN1; SMN2FAAHALDH1A1HSD17B10 | |
| SCHEMBL29059633 | 0.92 | LMNA (0.45) | LMNASMN1; SMN2FAAHALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL7879376 | 0.92 | LMNA (0.45) | LMNASMN1; SMN2FAAHALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL999467 | 0.92 | LMNA (0.45) | LMNASMN1; SMN2FAAHALDH1A1HSD17B10 | |
| SCHEMBL9949238 | 0.89 | LMNA (0.41) | LMNASMN1; SMN2ALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2498746-B1 | SKIN CARE COMPOSITIONS COMPRISING PHENOXYALKYL AMINES | UNILEVER PLC NO 41424 (GB) | 2016-08-24 | — | — | EP | disclosed |