SCHEMBL1799978

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12350612	0.88	HCRTR1 (0.45)	TRPV1HCRTR1HCRTR2MAP4K1
	SCHEMBL1800337	0.85	CHUK (0.40)	TRPV1ROCK2LPAR2P2RY14KCNH2
	SCHEMBL1797596	0.83	TRPV1 (0.52)	TRPV1ROCK2
	SCHEMBL1798709	0.83	TRPV1 (0.52)	TRPV1ROCK2
	SCHEMBL1800621	0.83	TRPV1 (0.52)	TRPV1ROCK2
	SCHEMBL1796493	0.83	TRPV1 (0.52)	TRPV1ROCK2
	SCHEMBL1797750	0.83	TRPV1 (0.52)	TRPV1ROCK2
	SCHEMBL12359141	0.83	ROCK2 (0.38)	PARP1TRPV1ROCK2LPAR2KCNH2
	SCHEMBL1796478	0.83	TRPV1 (0.40)	TRPV1ROCK2FPR2FPR1LPAR2
	SCHEMBL1800653	0.82	TRPV1 (0.52)	TRPV1ROCK2LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.