Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17999757 | 1.00 | SLC6A4 (0.56) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL17999754 | 1.00 | SLC6A4 (0.56) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL5308469 | 0.75 | SLC6A4 (0.51) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3521657 | 0.72 | SLC6A3 (0.56) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3516421 | 0.72 | SLC6A3 (0.56) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3516424 | 0.72 | SLC6A3 (0.56) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3516420 | 0.72 | SLC6A3 (0.56) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL5086938 | 0.72 | SLC6A3 (0.56) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3521655 | 0.72 | SLC6A3 (0.56) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3518063 | 0.72 | SLC6A3 (1.00) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976513-B1 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SUNOVION PHARMACEUTICALS INC (US) | 2016-08-24 | — | — | EP | claimed |