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Sugi Predict / Compounds / SCHEMBL17999963

SCHEMBL17999963

SCHEMBL17999963

C[Si](C)(C)c1ccc(N(c2ccc([Si](C)(C)C)cc2)c2ccc3c(c2)Oc2cccc4c(N(c5ccc([Si](C)(C)C)cc5)c5ccc([Si](C)(C)C)cc5)ccc-3c24)cc1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17999935 0.96 MEN1 (0.32) MEN1POLBKMT2AKDM4EMAPK1
SCHEMBL17999943 0.96 MEN1 (0.32) MEN1POLBKMT2AKDM4EMAPK1
SCHEMBL16282052 0.96 MEN1 (0.32) MEN1POLBKMT2AKDM4EMAPK1
SCHEMBL16282074 0.91 KDM4E (0.33) KDM4EMAPK1ATM
SCHEMBL17999958 0.88 KDM4E (0.31) KDM4EMAPK1ATM
SCHEMBL16282051 0.87 KDM4E (0.37) MEN1POLBKMT2AKDM4EMAPK1
SCHEMBL17999922 0.87 PDK2 (0.31) —
SCHEMBL17999962 0.84 ALOX5 (0.30) —
SCHEMBL17999952 0.84 KDM4E (0.35) MEN1POLBKMT2AKDM4EMAPK1
SCHEMBL25915568 0.84 KDM4E (0.36) MEN1POLBKMT2AKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160233428-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-11 — — US disclosed
US-20160233428-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-11 — — US disclosed