Biphenyl

Biphenyl

SCHEMBL18000012

O=P(O)(O)Oc1cccc(OP(=O)(O)O)c1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.69
INPPL1 O15357 6/20 0.58
INPP5A Q14642 5/20 0.58
GGPS1 O95749 1/20 0.47
GPR84 Q9NQS5 1/20 0.46
PTPN1 P18031 1/20 0.44
PTPN5 P54829 1/20 0.44
INPP5B P32019 2/20 0.44
HCRTR1 O43613 1/20 0.44
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
PDE3A Q14432 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
CA2 P00918 1/20 0.42
FDPS P14324 1/20 0.42
MMP8 P22894 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL2780711 1.00 SRC (0.69) SRCINPPL1INPP5AGGPS1GPR84
SCHEMBL12005085 0.94 SRC (0.67) SRCINPPL1INPP5AGGPS1GPR84
Phenyl Dihydrogen Phosphate SCHEMBL28050807 0.90 SRC (0.73) SRCINPPL1INPP5AGGPS1GPR84
Biphenyl SCHEMBL12978995 0.90 SRC (0.86) SRCINPPL1INPP5AGPR84PTPN5
Biphenyl SCHEMBL6118426 0.90 SRC (0.86) SRCINPPL1INPP5AGPR84PTPN5
SCHEMBL130697 0.89 INPPL1 (0.71) SRCINPPL1INPP5AINPP5BHCRTR1
Biphenyl SCHEMBL6141288 0.89 SRC (0.60) SRCINPPL1INPP5AGGPS1GPR84
Phosphoric Acid SCHEMBL28992406 0.87 INPPL1 (0.68) SRCINPPL1INPP5AINPP5BHCRTR1
SCHEMBL2214337 0.83 SRC (0.75) SRCINPPL1INPP5AGPR84PTPN5
Biphenyl SCHEMBL27733067 0.83 SRC (0.75) SRCINPPL1INPP5AGPR84PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3259298-A1 FLAME RETARDANT THERMOSET COMPOSITIONS FRX Polymers, Inc. (US) 2017-12-27 EP disclosed
US-20160244607-A1 FLAME RETARDANT THERMOSET COMPOSITIONS FRX POLYMERS, INC. 2016-08-25 US disclosed
WO-2016134369-A1 FLAME RETARDANT THERMOSET COMPOSITIONS FRX POLYMERS, INC. (US) 2016-08-25 WO disclosed