Biphenyl

Biphenyl

SCHEMBL6141288

O=P(O)(O)Oc1cccc(O)c1.c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.60
INPPL1 O15357 3/20 0.45
INPP5A Q14642 3/20 0.45
HSD17B1 P14061 5/20 0.44
HSD17B2 P37059 5/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C9 P11712 1/20 0.44
GGPS1 O95749 1/20 0.43
ESR1 P03372 2/20 0.42
ESR2 Q92731 2/20 0.42
GPR84 Q9NQS5 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
PTPN1 P18031 1/20 0.40
PTPN5 P54829 1/20 0.40
INPP5B P32019 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL999412 0.93 SRC (0.64) SRCINPPL1INPP5ACYP3A4CYP2C9
SCHEMBL29743077 0.91 SRC (0.59) SRCINPPL1INPP5ACYP3A4ESR1
SCHEMBL133534 0.91 SRC (0.59) SRCINPPL1INPP5ACYP3A4ESR1
Biphenyl SCHEMBL2780711 0.89 SRC (0.69) SRCINPPL1INPP5ACYP2C9GGPS1
Biphenyl SCHEMBL18000012 0.89 SRC (0.69) SRCINPPL1INPP5ACYP2C9GGPS1
SCHEMBL20854529 0.89 SRC (0.58) SRCINPPL1INPP5ACYP3A4ESR1
Naphthalene SCHEMBL9438226 0.88 SRC (0.57) SRCINPPL1INPP5AHSD17B1HSD17B2
Phenyl Dihydrogen Phosphate SCHEMBL1457869 0.87 SRC (0.73) SRCINPPL1INPP5ACYP3A4CYP2C9
SCHEMBL12005085 0.87 SRC (0.67) SRCINPPL1INPP5AGGPS1GPR84
Phenyl Dihydrogen Phosphate SCHEMBL6767193 0.87 SRC (0.73) SRCINPPL1INPP5ACYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0996678-B1 HALOGEN-FREE FLAME-RETARDANT THERMOPLASTIC POLYESTER OR POLYAMIDE COMPOSITION DSM IP ASSETS BV (NL) 2005-01-05 EP disclosed
US-6642288-B1 Organic high phosphorus content material and melamine resin derived from melam, melem or melon; effective at low concentration; improved crystallization; high stiffness DSM N.V. (NL) 2003-11-04 US disclosed