SCHEMBL180005

SCHEMBL180005

C1CCNC[N]C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285073 0.97
SCHEMBL18687 0.90
SCHEMBL674177 0.78 ALDH1A1 (0.60)
SCHEMBL3009 0.76
SCHEMBL567977 0.75 ALDH1A1 (0.56)
SCHEMBL175198 0.75
SCHEMBL566326 0.73 ALDH1A1 (0.53)
SCHEMBL675729 0.71 ALDH1A1 (0.50)
SCHEMBL235202 0.69
SCHEMBL7509079 0.69 ALDH1A1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814698-B2 Methods for simultaneous leaching and extraction of precious metals EXCIR WORKS CORP. (CA) 2023-11-14 US claimed
WO-2023151635-A1 COMPOUND BASED ON QUINAZOLINE-SUBSTITUTED GLUTARIMIDE SKELETON AND USE THEREOF 标新生物医药科技(上海)有限公司 2023-08-17 WO claimed
CN-116589445-A Compound based on quinazoline substituted glutarimide skeleton and application thereof 标新生物医药科技(上海)有限公司 2023-08-15 CN claimed
US-20220340998-A1 METHODS FOR SIMULTANEOUS LEACHING AND EXTRACTION OF PRECIOUS METALS EXCIR WORKS CORP. (CA) 2022-10-27 US claimed
US-11427886-B2 Methods for simultaneous leaching and extraction of precious metals EXCIR WORKS CORP. (CA) 2022-08-30 US claimed
CN-113969358-A Method for selective leaching and extraction of precious metals in organic solvents 艾克希尔工厂公司 2022-01-25 CN claimed
CN-108026608-B Method for selective leaching and extraction of precious metals in organic solvents 艾克希尔工厂公司 2021-10-22 CN claimed
EP-3770148-A1 RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF Beijing Tide Pharmaceutical Co., Ltd. (CN) 2021-01-27 EP claimed
CN-111801318-A Receptor inhibitors, pharmaceutical compositions comprising the same and uses thereof 北京泰德制药股份有限公司 2020-10-20 CN claimed
WO-2019179515-A1 RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF 北京泰德制药股份有限公司 2019-09-26 WO claimed
EP-1218372-A1 NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES Boehringer Ingelheim Pharmaceuticals, Inc. (US) 2002-07-03 EP claimed
US-20020058809-A1 Compounds useful as reversible inhibitors of cysteine proteases EMMANUEL MICHEL JOSE (US) 2002-05-16 US claimed
WO-2001019816-A1 NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2001-03-22 WO claimed
US-6100262-A MORPHOLINE RING NITROGEN IS SUBSTITUTED WITH A GROUP HAIVNG A CARBONYL FUNCTIONALITY; FAVOURABLE GASTROINTESTINAL MOTILITY STIMULATING PROPERTIES, THEY ACCELERATE GASTRIC EMPTYING JANSSEN PHARMACEUTICA, NV. (BE) 2000-08-08 US claimed
US-5756730-A Process for preparing analgesic compounds SANKYO COMPANY, LIMITED (JP) 1998-05-26 US claimed
EP-0827500-A1 (2-MORPHOLINYLMETHYL)BENZAMIDE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1998-03-11 EP claimed
US-5656758-A AMIDATION OF AN AMINE-CONTAINING THIOMORPHOLINE OR PIPERAZINE COMPOUND SANKYO COMPANY, LIMITED (JP) 1997-08-12 US claimed
WO-1996037486-A1 (2-MORPHOLINYLMETHYL)BENZAMIDE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1996-11-28 WO claimed
US-5025005-A Preventive or therapeutic agents for circulatory diseases, allergic disorders; antineoplastic agent; inhibitor for platelet activating factor TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-06-18 US claimed
US-4737518-A ANTIALLERGENS, ANTINEOPLASTICS, ANTICOAGULANTS, CIRCULATORY DISEASES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-04-12 US claimed