Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18005204 | 0.94 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL29833477 | 0.94 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL18005278 | 0.93 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL29833426 | 0.93 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL18005149 | 0.85 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL29833418 | 0.85 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL21083342 | 0.82 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL18030743 | 0.82 | TGFBR1 (0.86) | TGFBR1TGFBR2 | |
| SCHEMBL18005375 | 0.80 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL29833463 | 0.80 | TGFBR1 (1.00) | TGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3259264-A1 | GDF-8 INHIBITORS | Rigel Pharmaceuticals, Inc. (US) | 2017-12-27 | — | — | EP | claimed |
| WO-2016133838-A1 | GDF-8 INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2016-08-25 | — | — | WO | claimed |