Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20178960 | 0.84 | TGFBR1 (0.71) | TGFBR1TGFBR2 | |
| SCHEMBL18005091 | 0.79 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL29833483 | 0.79 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL29833451 | 0.78 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL18005244 | 0.78 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL18005149 | 0.77 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL29833418 | 0.77 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL18005187 | 0.76 | TGFBR1 (0.74) | TGFBR1 | |
| SCHEMBL18005202 | 0.76 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL29833427 | 0.76 | TGFBR1 (1.00) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3259264-A1 | GDF-8 INHIBITORS | Rigel Pharmaceuticals, Inc. (US) | 2017-12-27 | — | — | EP | claimed |
| WO-2016133838-A1 | GDF-8 INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2016-08-25 | — | — | WO | claimed |