Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29833462 | 0.94 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL18005210 | 0.94 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL29833475 | 0.93 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL18005285 | 0.93 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL18005384 | 0.82 | TGFBR1 (0.78) | TGFBR1TGFBR2 | |
| SCHEMBL18005435 | 0.81 | TGFBR1 (0.68) | TGFBR1TGFBR2 | |
| SCHEMBL20193890 | 0.80 | TGFBR1 (0.75) | TGFBR1TGFBR2 | |
| SCHEMBL18005128 | 0.80 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL29833452 | 0.80 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL18005284 | 0.80 | TGFBR1 (0.74) | TGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3259264-A1 | GDF-8 INHIBITORS | Rigel Pharmaceuticals, Inc. (US) | 2017-12-27 | — | — | EP | claimed |
| WO-2016133838-A1 | GDF-8 INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2016-08-25 | — | — | WO | claimed |