SCHEMBL1800595

SCHEMBL1800595

O=c1oc2ccccc2c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
KDM4E B2RXH2 5/20 0.50
CYP3A4 P08684 3/20 0.50
ALDH1A1 P00352 3/20 0.50
CYP19A1 P11511 2/20 0.50
HPGD P15428 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CA12 O43570 2/20 0.50
TP53 P04637 2/20 0.50
ABCB1 P08183 2/20 0.50
ADORA3 P0DMS8 2/20 0.50
AR P10275 2/20 0.50
CYP1B1 Q16678 2/20 0.50
CA9 Q16790 2/20 0.50
RAB9A P51151 2/20 0.50
MAOB P27338 2/20 0.50
ABCG2 Q9UNQ0 2/20 0.50
GABRP O00591 1/20 0.50
GABRD O14764 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13769238 0.90 MAOB (0.53) CA1CA2KDM4EALDH1A1SMN1; SMN2
SCHEMBL31511408 0.90 TNKS (0.53) CA1CA2CYP19A1RAB9AMAOB
SCHEMBL7463411 0.86 MAOB (0.72) CA1CA2KDM4ECYP3A4ALDH1A1
SCHEMBL31511409 0.86 MAOB (0.72) CA1CA2KDM4ECYP3A4ALDH1A1
SCHEMBL14506703 0.85 MAOB (0.55) KDM4EALDH1A1SMN1; SMN2TP53CA9
SCHEMBL28263851 0.84 ALDH1A1 (0.46) CA1CA2KDM4ECYP3A4ALDH1A1
SCHEMBL7124530 0.84 C1R (0.46) CA1CA2KDM4ECYP3A4ALDH1A1
SCHEMBL28859670 0.83 CA1 (0.51) CA1CA2KDM4ECYP3A4ALDH1A1
SCHEMBL4449250 0.83 ERAP1 (0.68) CA1CA2KDM4ECYP3A4ALDH1A1
SCHEMBL30014125 0.83 GAA (0.65) CA1CA2KDM4EALDH1A1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12083184-B2 Hydrogel prodrug for treatment VIKING SCIENTIFIC, INC. (US) 2024-09-10 US claimed
US-20240139111-A1 METHODS FOR THE EXTRACTION OF DISPERSIBLE MICROCAPSULES SPOROMEX LIMITED (GB) 2024-05-02 US disclosed
EP-4312996-A1 METHODS FOR THE EXTRACTION OF DISPERSIBLE MICROCAPSULES (IMMUNOCONTRACEPTION) Sporomex Limited (GB) 2024-02-07 EP disclosed
EP-4297735-A1 METHODS FOR THE EXTRACTION OF DISPERSIBLE MICROCAPSULES Sporomex Limited (GB) 2024-01-03 EP disclosed
CN-114349729-B Coumarin derivative and preparation method and application thereof 包头稀土研究院 2023-07-18 CN disclosed
CN-111349067-B Aggregation-induced emission type fluorescent material and preparation method thereof 陕西师范大学 2022-05-17 CN disclosed
CN-114349729-A Coumarin derivative and preparation method and application thereof 包头稀土研究院 2022-04-15 CN disclosed
CN-107973768-B Method for synthesizing coumarin compound in one step 江苏欣诺科催化剂有限公司 2020-11-10 CN disclosed
CN-111349067-A Aggregation-induced emission type fluorescent material and preparation method thereof 陕西师范大学 2020-06-30 CN disclosed
US-8828464-B2 Whitened exine shells UNIVERSITY OF HULL (GB) 2014-09-09 US disclosed
US-20110117148-A1 WHITENED EXINE SHELLS SPOROMEX LIMITED (GB) 2011-05-19 US disclosed