Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL18009262

CCCCC(CN)C[Si](OCC)(OCC)OCC.N

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP3A4 P08684 3/20 0.36
L3MBTL1 Q9Y468 1/20 0.34
TSHR P16473 2/20 0.31
OPRM1 P35372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18660483 0.87 ALDH1A1 (0.38) ALDH1A1TDP1CYP3A4
SCHEMBL9861818 0.85 ALDH1A1 (0.41) ALDH1A1TDP1CYP3A4L3MBTL1TSHR
SCHEMBL813630 0.82 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL906667 0.82 CYP3A4 (0.46) ALDH1A1TDP1CYP3A4L3MBTL1TSHR
SCHEMBL31682168 0.82 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL3125618 0.79
SCHEMBL7617988 0.78 ALDH1A1 (0.52) ALDH1A1TDP1CYP3A4L3MBTL1TSHR
SCHEMBL29276972 0.76 CYP3A4 (0.41) ALDH1A1TDP1CYP3A4L3MBTL1TSHR
SCHEMBL4428419 0.75 ALDH1A1 (0.40) ALDH1A1TDP1
SCHEMBL4435254 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3049483-B1 METAL EFFECT PIGMENTS MODIFIED WITH A SILANE LAYER CONTAINING AT LEAST TWO DIFFERENT BIFUNCTIONAL SILANES SCHLENK METALLIC PIGMENTS GMBH (DE) 2019-06-12 EP claimed
US-20160244615-A1 METAL EFFECT PIGMENTS MODIFIED WITH A SILANE LAYER CONTAINING AT LEAST TWO DIFFERENT BIFUNCTIONAL SILANES SCHLENK METALLIC PIGMENTS GMBH (DE) 2016-08-25 US claimed
US-20160244615-A1 METAL EFFECT PIGMENTS MODIFIED WITH A SILANE LAYER CONTAINING AT LEAST TWO DIFFERENT BIFUNCTIONAL SILANES SCHLENK METALLIC PIGMENTS GMBH (DE) 2016-08-25 US disclosed