⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38015 | 0.79 | CES1 (0.52) | — | |
| SCHEMBL10877617 | 0.79 | CES2 (0.52) | — | |
| SCHEMBL6567 | 0.79 | — | — | |
| SCHEMBL3281774 | 0.79 | CES2 (0.52) | — | |
| SCHEMBL3902058 | 0.79 | ESR1 (0.56) | — | |
| SCHEMBL11844374 | 0.79 | ESR1 (0.56) | — | |
| SCHEMBL1035354 | 0.79 | ESR1 (0.56) | — | |
| SCHEMBL23278527 | 0.76 | ESR1 (0.61) | — | |
| SCHEMBL21811153 | 0.76 | CES2 (0.50) | — | |
| SCHEMBL28658039 | 0.76 | CES2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3625219-A1 | PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLYLCARBOXYAMIDES | Bayer Aktiengesellschaft (DE) | 2020-03-25 | — | — | EP | claimed |
| CN-102482731-B | Method for recovering metals from aqueous solutions | CYTEC TECH CORP | 2015-06-10 | — | — | CN | claimed |
| EP-2091945-B1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2014-01-15 | — | — | EP | claimed |
| US-7705050-B2 | Amides, useful in the inhibition of IL-8-induced chemotaxis of neutrophils | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2010-04-27 | — | — | US | claimed |
| EP-1255726-B1 | (R)-2-ARYL-PROPIONAMIDES, USEFUL IN THE INHIBITION OF IL-8 INDUCED CHEMIOTAXIS OF NEUTROPHILS | DOMPE PHA R MA SPA RES & MFG (IT) | 2009-11-11 | — | — | EP | claimed |
| WO-2009131692-A1 | SUBSTRATES FOR DELIVERY OF PHYSIOLOGICALLY ACTIVE AGENTS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2009-10-29 | — | — | WO | claimed |
| US-7521476-B2 | Aminoacetonitrile derivatives suitable for controlling parasites | NOVARTIS AG (CH) | 2009-04-21 | — | — | US | claimed |
| US-7446219-B2 | N-acylaminoacetonitrile derivatives and their use for controlling parasites | NOVARTIS ANIMAL HEALTH US INC. (US) | 2008-11-04 | — | — | US | claimed |
| US-20080194693-A1 | Aminoacetonitrile Derivatives and Their Use for Controlling Parasites on Warm-Blooded Animals | NOVARTIS AG (CH) | 2008-08-14 | — | — | US | claimed |
| EP-1509221-B1 | N-ACYLAMINOACETONITRILE DERIVATIVES AND THEIR USE FOR CONTROLLING PARASITES | NOVARTIS AG (CH) | 2008-07-09 | — | — | EP | claimed |
| US-6376548-B1 | FUNGICIDES; HERBICIDES; INSECTICIDES | ROHM AND HAAS COMPANY | 2002-04-23 | — | — | US | claimed |
| WO-2001058852-A2 | (R)-2-ARYL-PROPIONAMIDES, USEFUL IN THE INHIBITION OF IL-8-INDUCED CHEMIOTAXIS OF NEUTROPHILS | Dompé S.p.A. (IT) | 2001-08-16 | — | — | WO | claimed |
| EP-0853626-A1 | SUBSTITUTED PHOSPHINIC COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Novartis AG (CH) | 1998-07-22 | — | — | EP | claimed |
| WO-1997009335-A1 | SUBSTITUTED PHOSPHINIC COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | NOVARTIS AG (CH) | 1997-03-13 | — | — | WO | claimed |
| EP-0113570-B1 | 5-(AMINO OR SUBSTITUTED AMINO) IMIDAZOLES | MERCK & CO. INC. (US) | 1987-02-25 | — | — | EP | claimed |
| EP-0113570-A1 | 5-(Amino or substituted amino) imidazoles | MERCK & CO. INC. (US) | 1984-07-18 | — | — | EP | claimed |
| EP-0037861-A1 | Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi | TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) | 1981-10-21 | — | — | EP | claimed |
| US-4255152-A | USING A DISPERSE DYE, WATER, AND AN ADDUCT OF ETHYLENE, PROPYLENE, OR STYRENE OXIDE AND A CYCLIC-SUBSTITUTED PHENOL; LEVELLING | CIBA-GEIGY CORPORATION (US) | 1981-03-10 | — | — | US | claimed |
| US-4127495-A | BENZYLHYDROXYETHYL CELLULOSE OR PHENYLHYDROXYETHYL HYDROXYETHYL CELLULOSE AS ANTI-REDEPOSITION ADDITIVES | HERCULES INCORPORATED (US) | 1978-11-28 | — | — | US | claimed |
| US-4065319-A | HYDRAULIC CEMENT, HYDROXYETHYL CELLULOSE WATER RETENTION AID ION | HERCULES INCORPORATED (US) | 1977-12-27 | — | — | US | claimed |