Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.35 |
| ▸ | ANPEP | P15144 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18009339 | 0.89 | PIK3CD (0.32) | — | |
| SCHEMBL18007449 | 0.86 | PIK3CD (0.36) | MMP2ANPEPHRH3 | |
| SCHEMBL18009205 | 0.79 | — | — | |
| SCHEMBL18009453 | 0.79 | — | — | |
| SCHEMBL18009450 | 0.78 | ATM (0.47) | MMP2ANPEPATM | |
| SCHEMBL18009458 | 0.78 | MMP2 (0.54) | MMP2ANPEPATM | |
| SCHEMBL18009463 | 0.77 | MMP2 (0.42) | MMP2ANPEPATM | |
| SCHEMBL18009202 | 0.77 | MMP2 (0.42) | MMP2ANPEPATM | |
| SCHEMBL18009330 | 0.75 | HRH3 (0.38) | MMP2ANPEPHRH3 | |
| SCHEMBL18007446 | 0.75 | HRH3 (0.38) | MMP2ANPEPHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016127186-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | NGUYEN MARK QUANG (US) | 2016-08-11 | — | — | WO | disclosed |