SCHEMBL18010449

SCHEMBL18010449

NNC(=O)c1ccccc1O.NNC(=O)c1ccccc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.65
GAA P10253 3/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
MPO P05164 1/20 0.65
HIF1A Q16665 1/20 0.65
CA1 P00915 3/20 0.60
CA9 Q16790 3/20 0.60
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
MAPT P10636 3/20 0.60
CA2 P00918 2/20 0.60
MITF O75030 1/20 0.60
NCOA1 Q15788 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
NCOA3 Q9Y6Q9 1/20 0.60
LMNA P02545 6/20 0.59
ALDH1A1 P00352 6/20 0.59
HPGD P15428 5/20 0.59
HTT P42858 4/20 0.59
HSD17B10 Q99714 4/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30489955 1.00 KDM4E (0.65) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL161525 1.00 KDM4E (0.65) KDM4EGAASMN1; SMN2MPOHIF1A
Charcoal, Activated SCHEMBL31491463 0.98 KDM4E (0.63) KDM4EGAASMN1; SMN2MPOHIF1A
Alcohol SCHEMBL28211827 0.92 CTSD (0.58) KDM4EGAASMN1; SMN2MPOHIF1A
Succinic Acid SCHEMBL10615249 0.90 KDM4E (0.55) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL6550750 0.89 CA1 (0.54) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL8663287 0.88 GAA (0.53) KDM4EGAASMN1; SMN2MPOHIF1A
Adipic Acid SCHEMBL28607978 0.87 KDM4E (0.52) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL674925 0.86 KDM4E (0.50) KDM4EGAASMN1; SMN2MPOHIF1A
Water SCHEMBL8856810 0.86 GAA (0.50) KDM4EGAASMN1; SMN2MPOHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3081589-B1 BASE TO BE COATED HAVING IMPROVED COATING PROPERTIES ADEKA CORP (JP) 2021-09-08 EP disclosed
EP-3081589-A1 BASE TO BE COATED HAVING IMPROVED COATING PROPERTIES Adeka Corporation (JP) 2016-10-19 EP disclosed
US-20160244592-A1 SUBSTRATE WITH IMPROVED COATABILITY ADEKA CORPORATION (JP) 2016-08-25 US disclosed