Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12458543 | 0.89 | ELANE (0.54) | ELANEHPGDKDM4EALDH1A1NCEH1 | |
| SCHEMBL6346568 | 0.84 | KDM4E (0.47) | ELANEHPGDKDM4EALDH1A1NCEH1 | |
| SCHEMBL19335938 | 0.83 | KDM4E (0.39) | ELANEHPGDKDM4EALDH1A1NCEH1 | |
| SCHEMBL15302955 | 0.81 | NQO1 (0.50) | ELANEHPGDKDM4EALDH1A1NCEH1 | |
| SCHEMBL29497591 | 0.78 | ELANE (0.50) | ELANEHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL207636 | 0.78 | ELANE (0.50) | ELANEHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL2760999 | 0.78 | HPGD (0.46) | HPGDKDM4EALDH1A1NCEH1KMT2A | |
| SCHEMBL13374671 | 0.78 | GPR84 (0.49) | ELANEHPGDKDM4EALDH1A1NCEH1 | |
| SCHEMBL27609119 | 0.78 | ELANE (0.41) | ELANEHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL29801955 | 0.77 | ELANE (0.58) | ELANEKDM4EALDH1A1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3861039-B1 | HYDROGEL COMPOSITIONS | OPHTALMIC CIE (FR) | 2023-11-01 | — | — | EP | claimed |
| US-20210332174-A1 | HYDROGEL COMPOSITIONS | OPHTALMIC COMPAGNIE (FR) | 2021-10-28 | — | — | US | claimed |
| EP-3861039-A1 | HYDROGEL COMPOSITIONS | Ophtalmic Compagnie (FR) | 2021-08-11 | — | — | EP | claimed |
| CN-113166340-A | Hydrogel composition | 眼科公司 | 2021-07-23 | — | — | CN | claimed |
| WO-2020070423-A1 | HYDROGEL COMPOSITIONS | OPHTALMIC COMPAGNIE (FR) | 2020-04-09 | — | — | WO | claimed |
| EP-1095076-A4 | INTERPENETRATING POLYMER NETWORK HYDROPHILIC HYDROGELS FOR CONTACT LENS | SUNSOFT CORP (US) | 2002-11-06 | — | — | EP | claimed |
| US-20010044482-A1 | Interpenetrating polymer network hydrophilic hydrogels for contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2001-11-22 | — | — | US | claimed |
| EP-1095076-A1 | INTERPENETRATING POLYMER NETWORK HYDROPHILIC HYDROGELS FOR CONTACT LENS | Sunsoft Corporation (US) | 2001-05-02 | — | — | EP | claimed |
| WO-2000002937-A1 | INTERPENETRATING POLYMER NETWORK HYDROPHILIC HYDROGELS FOR CONTACT LENS | SUNSOFT CORPORATION (US) | 2000-01-20 | — | — | WO | claimed |
| EP-0080539-B1 | POLYMERS PRIMARILY FOR CONTACT LENSES, AND CONTACT LENSES MADE FROM THEM | Tsuetaki, George F. (US) | 1986-05-07 | — | — | EP | claimed |
| EP-0080539-A1 | Polymers primarily for contact lenses, and contact lenses made from them | Tsuetaki, George F. (US) | 1983-06-08 | — | — | EP | claimed |
| WO-1983001777-A1 | IMPROVED OXYGEN PERMEABLE HARD AND SEMI-HARD CONTACT LENS COMPOSITIONS, METHODS AND ARTICLES OF MANUFACTURE | TSUETAKI GEORGE F (US) | 1983-05-26 | — | — | WO | claimed |
| EP-0067254-A1 | Oxygen permeable hard and semi-hard contact lens compositions, processes for their preparation, contact lenses and their manufacture from such compositions | SYNTEX (U.S.A.) INC. (US) | 1982-12-22 | — | — | EP | claimed |
| US-4303772-A | COPOLYMER OF POLYSILOXANYL ALKYL ACRYLATES OR METHACRYLATES, FREE RADICAL CATALYST | Tsuetaki, George F. (US) | 1981-12-01 | — | — | US | claimed |
| US-4248989-A | MACHINABLE, DIMENSIONALLY STABLE | SYNTEX OPHTHALMICS, INC., | 1981-02-03 | — | — | US | claimed |
| EP-3861039-B1 | HYDROGEL COMPOSITIONS | OPHTALMIC CIE (FR) | 2023-11-01 | — | — | EP | disclosed |
| US-20210332174-A1 | HYDROGEL COMPOSITIONS | OPHTALMIC COMPAGNIE (FR) | 2021-10-28 | — | — | US | disclosed |
| US-4303772-A | COPOLYMER OF POLYSILOXANYL ALKYL ACRYLATES OR METHACRYLATES, FREE RADICAL CATALYST | Tsuetaki, George F. (US) | 1981-12-01 | — | — | US | disclosed |
| US-4248989-A | MACHINABLE, DIMENSIONALLY STABLE | SYNTEX OPHTHALMICS, INC., | 1981-02-03 | — | — | US | disclosed |
| US-4242483-A | FROM AN UNSATURATED SILICON CONTAINING MONOMER AND AN ACRYLIC OR METHACRYLIC ESTER OR ITACONATE ESTER | SYNTEX OPHTHALMICS, INC., | 1980-12-30 | — | — | US | disclosed |