Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11977584 | 0.95 | CTSK (0.45) | KMT2APOLBL3MBTL1NOD1CTSK | |
| SCHEMBL14079862 | 0.95 | CTSK (0.45) | KMT2APOLBL3MBTL1NOD1CTSK | |
| SCHEMBL21992134 | 0.90 | KMT2A (0.47) | KMT2APOLBL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL11977586 | 0.89 | CTSK (0.40) | KMT2APOLBL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL10089716 | 0.86 | PRSS1 (0.40) | KMT2APOLBL3MBTL1CTSKCCKBR | |
| SCHEMBL25500375 | 0.86 | PRSS1 (0.40) | KMT2APOLBL3MBTL1CTSKCCKBR | |
| SCHEMBL30185954 | 0.86 | CTSK (0.45) | NOD1CTSKCTSS | |
| SCHEMBL16374717 | 0.85 | CTSK (0.40) | KMT2APOLBNOD1CTSKCTSS | |
| SCHEMBL29762744 | 0.85 | SELL (0.43) | CTSKCTSS | |
| SCHEMBL23972673 | 0.84 | GLP1R (0.44) | KMT2AL3MBTL1NOD1TDP1P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160228587-A1 | LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), THEIR USE AS IMAGING AGENTS AND PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PROSTATE CANCER | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160228587-A1 | LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), THEIR USE AS IMAGING AGENTS AND PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PROSTATE CANCER | KLK3, FOLH1, PSMA1 | KMT2A 2358/4885POLB 2629/4885L3MBTL1 4239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.