SCHEMBL18012277

SCHEMBL18012277

c1ccc(N(c2ccc3c(c2)N(c2cccc4ccccc24)c2cccc4c(N(c5ccccc5)c5cccc6ccccc56)ccc-3c24)c2cccc3ccccc23)cc1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.35
▸ SIGMAR1 Q99720 4/20 0.34
▸ ELANE P08246 1/20 0.32
▸ ENPP2 Q13822 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ USP2 O75604 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16491579 0.86 MEN1 (0.34) MEN1USP2KMT2A
SCHEMBL13507675 0.86 POLB (0.40) POLBSIGMAR1ELANEENPP2
SCHEMBL16491489 0.83 USP2 (0.40) POLBMEN1USP2KMT2A
SCHEMBL16491524 0.82 MEN1 (0.36) MEN1USP2KMT2A
SCHEMBL13507523 0.78 SIGMAR1 (0.36) SIGMAR1
SCHEMBL13085832 0.77 POLB (0.35) POLBSIGMAR1ELANEENPP2MEN1
SCHEMBL16491528 0.77 MEN1 (0.33) MEN1USP2KMT2A
SCHEMBL13085858 0.76 POLB (0.35) POLBSIGMAR1ELANEENPP2MEN1
SCHEMBL18859106 0.76 PDE6D (0.44) POLBSIGMAR1MEN1USP2KMT2A
SCHEMBL16491492 0.76 MEN1 (0.37) MEN1USP2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320195-A1 Electroactive Materials LG CHEM, LTD. (KR) 2023-10-05 — — US disclosed
US-20230320195-A1 Electroactive Materials LG CHEM, LTD. (KR) 2023-10-05 — — US disclosed
US-11683979-B2 Electroactive materials LG CHEM, LTD. 2023-06-20 — — US disclosed
US-11683979-B2 Electroactive materials LG CHEM, LTD. 2023-06-20 — — US disclosed
US-20180062082-A1 ELECTROACTIVE MATERIALS LG CHEM, LTD. (KR) 2018-03-01 — — US disclosed
US-20180062082-A1 ELECTROACTIVE MATERIALS LG CHEM, LTD. (KR) 2018-03-01 — — US disclosed
WO-2016126423-A2 ELECTROACTIVE MATERIALS E I DU PONT DE NEMOURS AND COMPANY (US) 2016-08-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180062082-A1 ELECTROACTIVE MATERIALS NR4A3, NCOA4, NR4A2 POLB 3301/4885SIGMAR1 1103/4885ELANE 2518/4885
US-20230320195-A1 Electroactive Materials NR4A3, NCOA4, NR4A2 POLB 3301/4885SIGMAR1 1103/4885ELANE 2518/4885
US-11683979-B2 Electroactive materials NR4A3, NCOA4, NR4A2 POLB 3376/4885SIGMAR1 1200/4885ELANE 2641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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