Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.64 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18013114 | 0.94 | SCN9A (0.65) | SCN9ASCN5A | |
| SCHEMBL18013112 | 0.93 | SCN9A (0.61) | SCN9ASCN5A | |
| SCHEMBL18013369 | 0.93 | SCN9A (0.54) | SCN9ASCN5A | |
| SCHEMBL18013105 | 0.92 | SCN9A (0.62) | SCN9ASCN5A | |
| SCHEMBL18013117 | 0.92 | SCN9A (0.67) | SCN9ASCN5A | |
| SCHEMBL18013370 | 0.92 | SCN5A (0.61) | SCN9ASCN5A | |
| SCHEMBL28888121 | 0.92 | SCN5A (0.61) | SCN9ASCN5A | |
| SCHEMBL18013275 | 0.91 | SCN9A (0.59) | SCN9ASCN5A | |
| SCHEMBL18013109 | 0.91 | SCN9A (0.59) | SCN9ASCN5A | |
| SCHEMBL18013113 | 0.91 | SCN9A (0.59) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016124139-A1 | HETEROCYCLIC-SUBSTITUTED N-SULFONYLBENZAMIDE DERIVATIVES, PREPARATION METHOD FOR DERIVATIVES, AND PHARMACEUTICAL USE OF DERIVATIVES | 上海海雁医药科技有限公司 | 2016-08-11 | — | — | WO | disclosed |