Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16333723 | 0.87 | LCK (0.55) | HTTTSHRLCKFYNCA9 | |
| SCHEMBL30390198 | 0.84 | KDM4E (0.46) | HTTTSHRLCKFYNCA9 | |
| SCHEMBL18512318 | 0.84 | KDM4E (0.46) | HTTTSHRLCKFYNCA9 | |
| SCHEMBL20601577 | 0.83 | TSHR (0.40) | HTTCYP3A4TSHRFYNPTGDR2 | |
| SCHEMBL22842606 | 0.80 | HTT (0.47) | HTTCYP3A4TSHRCA9LMNA | |
| SCHEMBL18013428 | 0.80 | HTT (0.47) | HTTCYP3A4TSHRCA9LMNA | |
| SCHEMBL23329394 | 0.79 | MTNR1A (0.38) | LCKFYNRAB9ANNMTKDM4E | |
| SCHEMBL20855840 | 0.76 | CYP3A4 (0.46) | HTTCYP3A4TSHRPTGDR2CA9 | |
| SCHEMBL1977994 | 0.76 | HTT (0.41) | HTTCYP3A4TSHRPTGDR2CA9 | |
| SCHEMBL18361718 | 0.75 | LCK (0.53) | TSHRLCKFYNCA9NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3255042-B1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | BEYONDBIO INC (KR) | 2020-12-30 | — | — | EP | disclosed |
| WO-2016126085-A2 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 비욘드바이오주식회사 | 2016-08-11 | — | — | WO | disclosed |