SCHEMBL1801550

SCHEMBL1801550

C=C(C(=O)O)C(CCC)[Si](C)(C)O[Si](C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3768511 0.91
SCHEMBL8467725 0.86
SCHEMBL18839808 0.79 CHRM1 (0.34) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL6545386 0.75
SCHEMBL3782689 0.75 CHRM1 (0.34) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL15939664 0.75 CHRM1 (0.34) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL440248 0.72 LMNA (0.31)
SCHEMBL8503776 0.71 CHRM1 (0.34) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL6448116 0.71
SCHEMBL9065140 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0657751-B1 Soft ocular lens material MENICON CO LTD (JP) 2003-04-23 EP claimed
US-8927618-B2 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens MENICON CO., LTD. (JP) 2015-01-06 US disclosed
US-8662663-B2 Hybrid soft contact lens, and production method and hydration treatment method thereof MENICON CO., LTD. (JP) 2014-03-04 US disclosed
US-20110116034-A1 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens MENICON CO., LTD. (JP) 2011-05-19 US disclosed
US-7261844-B2 For effectively reducing a period of time for discoloring a contact lens from a colored state to an uncolored state MENICON CO., LTD. (JP) 2007-08-28 US disclosed
US-20050243273-A1 Photochromic contact lens having excellent discoloring characteristic MENICON CO., LTD. (JP) 2005-11-03 US disclosed
US-5519070-A FLUORINE, ALKOXY POLYSILOXANE COPOLYMERS FOR INTRAOCULAR LENSES MENICON CO., LTD. (JP) 1996-05-21 US disclosed