Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 6/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19762758 | 0.92 | PDE10A (0.35) | PDE10ADDR1USP1SLC34A1EGLN1 | |
| SCHEMBL18498843 | 0.88 | PDE10A (0.38) | PDE10ADDR1EGLN1RORCS1PR1 | |
| SCHEMBL17949562 | 0.87 | SMN1; SMN2 (0.32) | DDR1CNR2KCNH2 | |
| SCHEMBL17949386 | 0.86 | PDE10A (0.35) | PDE10ADDR1CNR2KCNH2 | |
| SCHEMBL21020024 | 0.86 | DDR1 (0.33) | PDE10ADDR1CNR2KCNH2 | |
| SCHEMBL20465862 | 0.85 | PTGER4 (0.34) | DDR1CNR2KCNH2 | |
| SCHEMBL19366981 | 0.85 | EGLN1 (0.33) | PDE10ADDR1USP1EGLN1RORC | |
| SCHEMBL17949520 | 0.84 | DDR1 (0.35) | DDR1 | |
| SCHEMBL21020026 | 0.84 | KCNH2 (0.33) | DDR1CNR2KCNH2 | |
| SCHEMBL18498626 | 0.84 | POLB (0.41) | PDE10ADDR1USP1SLC34A1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3253210-B1 | 2-(HET) ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-11-24 | — | — | EP | disclosed |
| CN-107428764-B | 2- (hetero) aryl-substituted fused bicyclic heterocyclic derivatives as pest control agents | 拜耳作物科学股份公司 | 2020-09-11 | — | — | CN | disclosed |
| WO-2016124563-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHSAFT (DE) | 2016-08-11 | — | — | WO | disclosed |