Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 8/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19762758 | 0.89 | PDE10A (0.35) | PDE10ADDR1RORCS1PR1EGLN1 | |
| SCHEMBL18015922 | 0.88 | PDE10A (0.35) | PDE10ADDR1RORCS1PR1EGLN1 | |
| SCHEMBL17383123 | 0.87 | DDR1 (0.36) | DDR1PDE2ARORCAGPAT2S1PR1 | |
| SCHEMBL18498626 | 0.86 | POLB (0.41) | PDE10ADDR1EGLN1 | |
| SCHEMBL17383211 | 0.85 | DDR1 (0.40) | DDR1PDE2ARORCAGPAT2S1PR1 | |
| SCHEMBL17382581 | 0.84 | DDR1 (0.42) | DDR1PDE2ARORCAGPAT2 | |
| SCHEMBL18498926 | 0.83 | AGPAT2 (0.41) | DDR1PDE2ARORCAGPAT2 | |
| SCHEMBL17382833 | 0.82 | GRM2 (0.44) | DDR1PDE2ARORCAGPAT2 | |
| SCHEMBL18498707 | 0.82 | KDM4E (0.39) | DDR1PDE2ARORCAGPAT2 | |
| SCHEMBL18506068 | 0.82 | PDE10A (0.39) | PDE10ADDR1PDE2AAGPAT2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955472-A | 2- (Hetero) aryl substituted fused heterocyclic derivatives as pesticides | 拜耳作物科学股份公司 | 2024-11-15 | — | — | CN | disclosed |
| EP-3896065-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3896066-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3896065-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3896066-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3331870-B1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| EP-3331870-B1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-04-27 | — | — | US | disclosed |
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-04-27 | — | — | US | disclosed |
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-02 | — | — | US | disclosed |
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-02 | — | — | US | disclosed |
| US-20200029567-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20200029567-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20180271099-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-09-27 | — | — | US | disclosed |
| EP-3331870-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-06-13 | — | — | EP | disclosed |
| WO-2017025419-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | WO | disclosed |
| WO-2017025419-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | PDE10A 2304/4885DDR1 2548/4885PDE2A 1762/4885 |
| US-20200029567-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | PDE10A 2304/4885DDR1 2548/4885PDE2A 1762/4885 |
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | PDE10A 2304/4885DDR1 2548/4885PDE2A 1762/4885 |
| US-20180271099-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | PDE10A 2304/4885DDR1 2548/4885PDE2A 1762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.