⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (+/-)-Tulipaline B SCHEMBL1073177 | 0.70 | — | — | |
| SCHEMBL2376391 | 0.70 | — | — | |
| SCHEMBL3947301 | 0.70 | — | — | |
| SCHEMBL3944987 | 0.70 | — | — | |
| (+/-)-Tulipaline B SCHEMBL4926880 | 0.70 | — | — | |
| SCHEMBL486362 | 0.69 | — | — | |
| SCHEMBL3960005 | 0.69 | — | — | |
| SCHEMBL9462518 | 0.69 | — | — | |
| SCHEMBL23914271 | 0.67 | CYP19A1 (0.51) | — | |
| Bromide SCHEMBL932220 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899365-B1 | ANGIOTENSIN I-CONVERTING ENZYME (ACE) INHIBITORS | UNIV CAPE TOWN (ZA) | 2012-09-12 | — | — | EP | disclosed |
| US-7981922-B2 | Angiotensin I-converting enzyme (ACE) inhibitors | UNIVERSITY OF CAPE TOWN (ZA) | 2011-07-19 | — | — | US | disclosed |
| US-7951834-B2 | Angiotensin I-converting enzyme (ACE) inhibitors | UNIVERSITY OF CAPE TOWN (ZA) | 2011-05-31 | — | — | US | disclosed |
| EP-1893633-B1 | ANGIOTENSIN I - CONVERTING ENZYME (ACE) INHIBITORS | UNIV CAPE TOWN (ZA) | 2010-09-01 | — | — | EP | disclosed |
| US-20090281160-A1 | Angiotensin I-converting enzyme (ace) inhibitors | ANGIODESIGN (UK) LIMITED (GB) | 2009-11-12 | — | — | US | disclosed |
| US-20090118351-A1 | Angiotensin I-Converting Enzyme (ACE) Inhibitors | ANGIODESIGN (UK) LIMITED (GB) | 2009-05-07 | — | — | US | disclosed |
| EP-1899365-A2 | ANGIOTENSIN I-CONVERTING ENZYME (ACE) INHIBITORS | University of Cape Town (ZA) | 2008-03-19 | — | — | EP | disclosed |
| EP-1893633-A2 | ANGIOTENSIN I - CONVERTING ENZYME (ACE) INHIBITORS | University of Cape Town (ZA) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006126086-A2 | ANGIOTENSIN I - CONVERTING ENZYME (ACE) INHIBITORS | UNIVERSITY OF CAPE TOWN (ZA) | 2006-11-30 | — | — | WO | disclosed |
| WO-2006126087-A2 | ANGIOTENSIN I-CONVERTING ENZYME (ACE) INHIBITORS | UNIVERSITY OF CAPE TOWN (ZA) | 2006-11-30 | — | — | WO | disclosed |