Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9462518 | 0.97 | — | — | |
| SCHEMBL3960005 | 0.97 | — | — | |
| SCHEMBL486362 | 0.97 | — | — | |
| SCHEMBL16641900 | 0.94 | BLM (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL9463168 | 0.77 | OAT (0.37) | — | |
| Trifluoroacetic Acid SCHEMBL9462962 | 0.77 | OAT (0.37) | — | |
| SCHEMBL981852 | 0.71 | — | — | |
| Homoserine Lactone SCHEMBL1034274 | 0.69 | — | — | |
| Homoserine Lactone SCHEMBL7217249 | 0.69 | — | — | |
| Homoserine Lactone SCHEMBL1536657 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448930-A1 | COVALENT INHIBITION OF BACTERIAL QUORUM SENSING | The National Institute for Biotechnology in the Negev Ltd. (IL) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001419-A1 | COVALENT INHIBITION OF BACTERIAL QUORUM SENSING | NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV (IL) | 2011-01-06 | — | — | WO | disclosed |