Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1652973 | 1.00 | KMT2A (0.50) | KMT2ATSHRMAPK1BTKALDH1A1 | |
| SCHEMBL1652976 | 1.00 | KMT2A (0.50) | KMT2ATSHRMAPK1BTKALDH1A1 | |
| SCHEMBL12076600 | 0.91 | TSHR (0.48) | KMT2ATSHRMAPK1BTKALDH1A1 | |
| SCHEMBL1651799 | 0.86 | KDM4E (0.45) | ALDH1A1KDM4EGAA | |
| SCHEMBL12654462 | 0.86 | ALDH1A1 (0.45) | KMT2ATSHRMAPK1BTKALDH1A1 | |
| SCHEMBL1650724 | 0.86 | KDM4E (0.45) | ALDH1A1KDM4EGAA | |
| SCHEMBL1651250 | 0.85 | BTK (0.43) | KMT2ATSHRMAPK1BTKALDH1A1 | |
| SCHEMBL1651251 | 0.85 | BTK (0.43) | KMT2ATSHRMAPK1BTKALDH1A1 | |
| SCHEMBL1650318 | 0.85 | BTK (0.44) | KMT2ATSHRMAPK1BTKALDH1A1 | |
| SCHEMBL1650320 | 0.85 | BTK (0.44) | KMT2ATSHRMAPK1BTKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493304-A1 | SPIROLACTAM DERIVATIVES AND USES OF SAME | H. Lundbeck A/S (DK) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011053575-A1 | SPIROLACTAM DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2011-05-05 | — | — | WO | disclosed |