⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180189 | 0.87 | — | — | |
| SCHEMBL179880 | 0.84 | — | — | |
| SCHEMBL4828336 | 0.84 | TSHR (0.33) | — | |
| SCHEMBL6245017 | 0.84 | TSHR (0.33) | — | |
| SCHEMBL179988 | 0.84 | — | — | |
| SCHEMBL3836831 | 0.84 | — | — | |
| SCHEMBL6243787 | 0.84 | TSHR (0.33) | — | |
| SCHEMBL6246251 | 0.84 | TSHR (0.33) | — | |
| SCHEMBL6240386 | 0.84 | TSHR (0.33) | — | |
| SCHEMBL103016 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2377 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486929-A | Substituted alkyl germanium compound and modularized synthesis method thereof | 西安交通大学 | 2024-02-02 | — | — | CN | claimed |
| CN-117154159-A | Oxidation-resistant durable high-temperature proton exchange membrane for fuel cell and preparation method thereof | 吴礼鸿 | 2023-12-01 | — | — | CN | claimed |
| CN-115894317-A | Micromolecular compound with naphthylthiophenol ether structure and application thereof | 杭州天玑济世生物科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115894404-A | Micromolecular compound with naphthylamine structure and application thereof | 杭州天玑济世生物科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| WO-2023045909-A1 | SMALL MOLECULE COMPOUNDS HAVING NAPHTHYLAMINE STRUCTURE AND APPLICATION THEREOF | 杭州天玑济世生物科技有限公司 | 2023-03-30 | — | — | WO | claimed |
| WO-2023045910-A1 | SMALL-MOLECULE COMPOUND HAVING NAPHTHOL ETHER STRUCTURE, AND USE THEREOF | 杭州天玑济世生物科技有限公司 | 2023-03-30 | — | — | WO | claimed |
| CN-106117139-A | A kind of enhancement mode fluorescent probe and preparation method and application | 华南理工大学 | 2016-11-16 | — | — | CN | claimed |
| JP-4537315-B2 | — | — | 2010-09-01 | — | — | JP | claimed |
| US-7666863-B2 | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases | VIROPHARMA INCORPORATED (US) | 2010-02-23 | — | — | US | claimed |
| US-20080306096-A1 | Quinazoline Derivatives, Process for Their Preparation and Their Use as Anti-Cancer Agents | ASTRAZENECA AB (SE) | 2008-12-11 | — | — | US | claimed |
| EP-1409481-B1 | QUINOLINE DERIVATIVES AND THEIR USE AS TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2006-10-04 | — | — | EP | claimed |
| JP-2006510736-A | — | — | 2006-03-30 | — | — | JP | claimed |
| CN-1731993-A | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases | VIROPHARMA INC (US) | 2006-02-08 | — | — | CN | claimed |
| WO-2005112640-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES | VIROPHARMA INCORPORATED (US) | 2005-12-01 | — | — | WO | claimed |
| EP-1581207-A2 | BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES | Viropharma Incorporated (US) | 2005-10-05 | — | — | EP | claimed |
| US-20050009867-A1 | Quinoline derivatives and their use as tyrosine kinase inhibitors | ASTRAZENECA AB (SE) | 2005-01-13 | — | — | US | claimed |
| US-20040162318-A1 | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases | VIROPHARMA INCORPORATED | 2004-08-19 | — | — | US | claimed |
| WO-2004041201-A2 | BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES | VIROPHARMA INCORPORATED (US) | 2004-05-21 | — | — | WO | claimed |
| EP-1409481-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS TYROSINE KINASE INHIBITORS | Astrazeneca AB (SE) | 2004-04-21 | — | — | EP | claimed |
| WO-2003008409-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2003-01-30 | — | — | WO | claimed |