Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA4 | P22748 | 2/20 | 0.57 |
| ▸ | CA5A | P35218 | 2/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871587 | 0.89 | KDM4E (0.52) | CA12CA1CA2CA4CA5A | |
| SCHEMBL916913 | 0.86 | CA12 (0.71) | CA12CA1CA2CA4CA5A | |
| SCHEMBL2673237 | 0.85 | CA12 (0.57) | CA12CA1CA2CA4CA5A | |
| SCHEMBL1823387 | 0.85 | CA12 (0.57) | CA12CA1CA2CA4CA5A | |
| SCHEMBL1818246 | 0.85 | KDM4E (0.66) | CA12CA1CA2CA4CA5A | |
| SCHEMBL23805149 | 0.81 | CXCR3 (0.58) | CA12CA1CA2CA4CA5A | |
| SCHEMBL23649978 | 0.80 | CA12 (0.60) | CA12CA1CA2CA4CA5A | |
| SCHEMBL18609760 | 0.80 | CA12 (0.57) | CA12CA1CA2CA4CA5A | |
| SCHEMBL7725283 | 0.79 | CA12 (0.62) | CA12CA1CA2CA4CA5A | |
| SCHEMBL13202954 | 0.77 | CARM1 (0.62) | SIGMAR1ALDH1A1GAACARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060271-A1 | SCREENING FOR INHIBITORS OF P. FALCIPARUM USING LUCIFERASE BASED HIGH THROUGHPUT SCREENING ASSAY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011060271-A1 | SCREENING FOR INHIBITORS OF P. FALCIPARUM USING LUCIFERASE BASED HIGH THROUGHPUT SCREENING ASSAY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-05-19 | — | — | WO | disclosed |