Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 18/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17979058 | 0.87 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL17979061 | 0.87 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL18016256 | 0.86 | ADRB2 (0.39) | ADRB2ADRB1ADRB3 | |
| SCHEMBL19784365 | 0.85 | ADRB2 (0.42) | ADRB2ADRB1ADRB3 | |
| SCHEMBL22839965 | 0.82 | ADRB2 (0.54) | ADRB2ADRB1ADRB3 | |
| SCHEMBL19784007 | 0.80 | HDAC1 (0.42) | ADRB2ADRB1ADRB3 | |
| SCHEMBL19770230 | 0.79 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL17978784 | 0.78 | ADRB2 (0.39) | ADRB2ADRB1ADRB3 | |
| SCHEMBL17979195 | 0.78 | ADRB2 (0.39) | ADRB2ADRB1ADRB3 | |
| SCHEMBL18016255 | 0.78 | ADRB2 (0.38) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016128456-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-08-18 | — | — | WO | disclosed |