Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 7/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13301165 | 0.98 | ALDH1A1 (0.42) | ALDH1A1FKBP1ACA1CA2POLB | |
| SCHEMBL13816965 | 0.93 | ALDH1A1 (0.39) | ALDH1A1FKBP1ACA1CA2POLB | |
| SCHEMBL16508745 | 0.80 | CA1 (0.46) | ALDH1A1FKBP1ACA1CA2POLB | |
| SCHEMBL11936225 | 0.80 | SMN1; SMN2 (0.38) | ALDH1A1POLBKMT2ATSHRNPSR1 | |
| SCHEMBL21361488 | 0.79 | ALDH1A1 (0.49) | ALDH1A1FKBP1ACA1CA2POLB | |
| SCHEMBL8281581 | 0.78 | CA12 (0.48) | ALDH1A1POLBTSHRSMN1; SMN2KDM4E | |
| SCHEMBL25541434 | 0.78 | KDM4E (0.42) | ALDH1A1KMT2ATSHRUSP2KDM4E | |
| SCHEMBL2029967 | 0.78 | PPARA (0.46) | ALDH1A1FKBP1ACA1CA2KMT2A | |
| SCHEMBL6755409 | 0.77 | ALDH1A1 (0.49) | ALDH1A1FKBP1ACA1CA2POLB | |
| SCHEMBL27708697 | 0.77 | ALDH1A1 (0.45) | ALDH1A1FKBP1ACA1CA2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016130501-A1 | AZA-HETEROARYL COMPOUNDS AS PI3K-GAMMA INHIBITORS | INCYTE CORPORATION (US) | 2016-08-18 | — | — | WO | disclosed |
| CN-1216056-C | Sulfamidohydroxamic acid metalloprotease inhibitor | SEARLE & CO (US) | 2005-08-24 | — | — | CN | disclosed |