Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11717752 | 0.98 | SIGMAR1 (0.48) | SIGMAR1HRH3CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL24098291 | 0.94 | SIGMAR1 (0.44) | SIGMAR1HRH3CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL18024013 | 0.92 | SIGMAR1 (0.47) | SIGMAR1HRH3CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL11730463 | 0.90 | SIGMAR1 (0.48) | SIGMAR1HRH3CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL20333472 | 0.90 | HRH3 (0.56) | SIGMAR1HRH3CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL791900 | 0.88 | SIGMAR1 (0.50) | SIGMAR1CYP1A2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18024081 | 0.86 | PAOX (0.43) | SIGMAR1TSHR | |
| SCHEMBL24722766 | 0.86 | HRH3 (0.48) | SIGMAR1HRH3CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL17517722 | 0.86 | SIGMAR1 (0.51) | SIGMAR1CYP1A2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17526223 | 0.86 | SIGMAR1 (0.55) | SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115243789-A | Catalyst composition for polyurethane | 迈图高新材料公司 | 2022-10-25 | — | — | CN | claimed |
| US-20230151136-A1 | CATALYST COMPOSITION FOR POLYURETHANES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2023-05-18 | — | — | US | disclosed |
| US-20230151136-A1 | CATALYST COMPOSITION FOR POLYURETHANES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2023-05-18 | — | — | US | disclosed |
| US-20230134280-A1 | CATALYSTS FOR THE FORMATION OF POLYURETHANES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2023-05-04 | — | — | US | disclosed |
| CN-115243789-A | Catalyst composition for polyurethane | 迈图高新材料公司 | 2022-10-25 | — | — | CN | disclosed |
| WO-2016130968-A1 | BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | YALE UNIVERSITY (US) | 2016-08-18 | — | — | WO | disclosed |