⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18009887 | 0.90 | ADORA3 (0.32) | — | |
| SCHEMBL18009748 | 0.89 | — | — | |
| SCHEMBL18026255 | 0.87 | PRMT5 (0.30) | — | |
| SCHEMBL18009857 | 0.86 | PRMT5 (0.33) | — | |
| SCHEMBL18026260 | 0.84 | — | — | |
| SCHEMBL18026250 | 0.84 | PI4KA (0.39) | — | |
| SCHEMBL18026253 | 0.84 | RXFP1 (0.32) | — | |
| SCHEMBL18026270 | 0.83 | PRMT5 (0.30) | — | |
| SCHEMBL18026254 | 0.81 | PRMT5 (0.31) | — | |
| SCHEMBL18009869 | 0.80 | PRMT5 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244475-A1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. (US) | 2016-08-25 | — | — | US | disclosed |