Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18028052 | 0.95 | ALDH1A1 (0.36) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL18426952 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL21128960 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL16629082 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL24501058 | 0.80 | ALDH1A1 (0.37) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL18773774 | 0.79 | TSHR (0.38) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL18028053 | 0.77 | ALDH1A1 (0.37) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL20878370 | 0.77 | ALDH1A1 (0.36) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL13282102 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL18747143 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRMAPTABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244494-A1 | STABILIZED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244494-A1 | STABILIZED POLYPEPTIDES AND USES THEREOF | JAK2, STAT5A, STAT3 | ALDH1A1 4698/4885LMNA 4344/4885TSHR 1222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.