Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.68 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13387542 | 0.83 | APP (0.63) | APPPTGER4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13387540 | 0.83 | APP (0.63) | APPPTGER4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL12479731 | 0.83 | APP (0.62) | APPPTGER4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL12479735 | 0.83 | APP (0.62) | APPPTGER4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL15911958 | 0.82 | MAPT (0.53) | APPPTGER4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29740692 | 0.82 | BCHE (0.53) | APPPTGER4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29740693 | 0.82 | BCHE (0.53) | APPPTGER4ALDH1A1SMN1; SMN2KDM4E | |
| Iodide SCHEMBL13387358 | 0.81 | APP (1.00) | APPPTGER4ALDH1A1SMN1; SMN2KDM4E | |
| Iodide SCHEMBL13387357 | 0.81 | APP (1.00) | APPPTGER4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13551414 | 0.80 | APP (0.98) | APPPTGER4ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795694-B2 | Imaging beta-amyloid peptides aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-10-24 | — | — | US | disclosed |
| US-20160243264-A1 | Imaging Beta-Amyloid Peptides Aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160243264-A1 | Imaging Beta-Amyloid Peptides Aggregation | APP, IAPP, APBA1 | APP 1/4885PTGER4 4526/4885ALDH1A1 3081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.