Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.62 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12479735 | 1.00 | APP (0.62) | APPPTGER4SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13551428 | 0.83 | APP (0.72) | APPPTGER4SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13387540 | 0.83 | APP (0.63) | APPPTGER4SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13387542 | 0.83 | APP (0.63) | APPPTGER4SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL18029443 | 0.83 | APP (0.68) | APPPTGER4SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13387565 | 0.82 | PTGER4 (0.85) | APPPTGER4SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12479908 | 0.82 | PTGER4 (0.85) | APPPTGER4SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30295042 | 0.82 | PTGER4 (0.85) | APPPTGER4SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12479798 | 0.81 | CNR2 (0.49) | CNR2 | |
| SCHEMBL12479793 | 0.81 | CNR2 (0.49) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170057946-A1 | CARBAZOLE END CAPPED BIPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-03-02 | — | — | US | claimed |
| EP-2663554-B1 | CARBAZOLE END CAPPED BIPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2016-05-18 | — | — | EP | claimed |
| EP-2663554-A1 | CARBAZOLE END CAPPED BIPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2013-11-20 | — | — | EP | claimed |
| WO-2012110945-A1 | CARBAZOLE END CAPPED BIPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-08-23 | — | — | WO | claimed |
| US-10144722-B2 | Carbazole end capped bipyridine compounds and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-12-04 | — | — | US | disclosed |
| US-20170057946-A1 | CARBAZOLE END CAPPED BIPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-03-02 | — | — | US | disclosed |
| EP-2663554-B1 | CARBAZOLE END CAPPED BIPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2016-05-18 | — | — | EP | disclosed |
| EP-2663554-A1 | CARBAZOLE END CAPPED BIPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2013-11-20 | — | — | EP | disclosed |
| WO-2012110945-A1 | CARBAZOLE END CAPPED BIPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170057946-A1 | CARBAZOLE END CAPPED BIPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | SLC39A3, SLC30A7, ZKSCAN2 | APP 3279/4885PTGER4 3024/4885SMN1; SMN2 3597/4885 |
| US-10144722-B2 | Carbazole end capped bipyridine compounds and process for preparation thereof | SLC39A3, SLC30A7, ZKSCAN2 | APP 3279/4885PTGER4 3024/4885SMN1; SMN2 3597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.