Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15911972 | 0.92 | APP (0.53) | APPMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL17955861 | 0.82 | APP (0.76) | APPMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL15910127 | 0.75 | APP (0.98) | APPMEN1RAB9AKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL15902009 | 0.75 | APP (1.00) | APPMEN1RAB9AKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL15902010 | 0.75 | APP (1.00) | APPMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL15911974 | 0.72 | CHAT (0.62) | APPMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL13551415 | 0.68 | APP (0.98) | APPMEN1RAB9AKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL13387549 | 0.67 | APP (1.00) | APPMEN1RAB9AKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL13387552 | 0.67 | APP (1.00) | APPMEN1RAB9AKMT2AALDH1A1 | |
| Iodide SCHEMBL4883351 | 0.66 | MEN1 (0.60) | APPMEN1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160243264-A1 | Imaging Beta-Amyloid Peptides Aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160243264-A1 | Imaging Beta-Amyloid Peptides Aggregation | APP, IAPP, APBA1 | APP 1/4885MEN1 304/4885RAB9A 2573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.