Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18029549 | 0.90 | PDE10A (0.39) | PDE10ACYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL24108459 | 0.87 | ESR1 (0.49) | CYP1A2ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL25787162 | 0.86 | ESR1 (0.44) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL12912438 | 0.85 | PDE10A (0.41) | PDE10ACYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL9976882 | 0.84 | PDE10A (0.43) | PDE10ACYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL15394376 | 0.83 | ALDH1A1 (0.42) | PDE10ACYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL15394602 | 0.82 | ALDH1A1 (0.41) | PDE10ACYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL18029493 | 0.82 | AHR (0.41) | CYP1A2KDM4EL3MBTL1ESR1ESR2 | |
| SCHEMBL18717961 | 0.82 | KDM4E (0.41) | CYP1A2ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL20864881 | 0.81 | ALDH1A1 (0.39) | PDE10ACYP1A2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3259786-B1 | SEMICONDUCTING MATERIAL AND NAPHTOFURANE MATRIX COMPOUND FOR IT | NOVALED GMBH (DE) | 2023-08-30 | — | — | EP | disclosed |
| US-11362285-B2 | Semiconducting material and naphthofurane matrix compound for it | NOVALED GMBH (DE) | 2022-06-14 | — | — | US | disclosed |
| US-20200280002-A1 | Semiconducting Material and Naphthofurane Matrix Compound for It | NOVALED GMBH (DE) | 2020-09-03 | — | — | US | disclosed |
| US-10658599-B2 | Semiconducting material and naphthofurane matrix compound for it | NOVALED GMBH (DE) | 2020-05-19 | — | — | US | disclosed |
| US-20180076397-A1 | Semiconducting Material and Naphtofurane Matrix Compound for It | NOVALED GMBH (DE) | 2018-03-15 | — | — | US | disclosed |
| US-20180076397-A1 | Semiconducting Material and Naphtofurane Matrix Compound for It | NOVALED GMBH (DE) | 2018-03-15 | — | — | US | disclosed |
| WO-2016131918-A1 | SEMICONDUCTING MATERIAL AND NAPHTOFURANE MATRIX COMPOUND FOR IT | NOVALED GMBH (DE) | 2016-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200280002-A1 | Semiconducting Material and Naphthofurane Matrix Compound for It | NES, NQO1, VIM | PDE10A 3617/4885CYP1A2 1253/4885ALDH1A1 1096/4885 |
| US-10658599-B2 | Semiconducting material and naphthofurane matrix compound for it | NES, NQO1, VIM | PDE10A 3617/4885CYP1A2 1253/4885ALDH1A1 1096/4885 |
| US-11362285-B2 | Semiconducting material and naphthofurane matrix compound for it | NES, NQO1, VIM | PDE10A 3617/4885CYP1A2 1253/4885ALDH1A1 1096/4885 |
| US-20180076397-A1 | Semiconducting Material and Naphtofurane Matrix Compound for It | NAPRT, NES, NAMPT | PDE10A 3475/4885CYP1A2 904/4885ALDH1A1 1490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.