SCHEMBL1803003

SCHEMBL1803003

CCCCOc1ccc(N)c2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2C19 P33261 1/20 0.62
IDO1 P14902 2/20 0.56
EP300 Q09472 1/20 0.55
KAT8 Q9H7Z6 1/20 0.55
CNR1 P21554 4/20 0.51
CNR2 P34972 4/20 0.51
GAA P10253 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
SLC2A1 P11166 1/20 0.48
TLR8 Q9NR97 1/20 0.46
MEN1 O00255 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
HTR1B P28222 2/20 0.45
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44
HTR1D P28221 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28047815 0.93 CYP2C9 (0.54) CYP2C9CYP1A2CYP2C19IDO1EP300
SCHEMBL11687927 0.91 IDO1 (0.58) CYP2C9CYP1A2CYP2C19IDO1EP300
SCHEMBL1806093 0.89 CYP2C9 (0.68) CYP2C9CYP1A2CYP2C19IDO1CNR1
SCHEMBL9770405 0.89 CNR1 (0.59) CYP2C9CYP1A2CYP2C19IDO1CNR1
SCHEMBL29502701 0.89 CNR1 (0.59) CYP2C9CYP1A2CYP2C19IDO1CNR1
SCHEMBL10605887 0.85 CNR1 (0.56) CYP2C9CYP1A2CYP2C19IDO1CNR1
SCHEMBL592706 0.84 IDO1 (0.53) CYP2C9CYP1A2CYP2C19IDO1EP300
SCHEMBL1806065 0.83 IDO1 (0.62) CYP1A2CYP2C19IDO1EP300KAT8
SCHEMBL10602032 0.83 CNR2 (0.55) CYP2C9CYP1A2CYP2C19CNR1CNR2
SCHEMBL29428922 0.83 CNR1 (0.55) CYP2C9CYP1A2CYP2C19IDO1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016159576-A2 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME 주식회사 케이티앤지생명과학 2016-10-06 WO disclosed
WO-2015102369-A1 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME 주식회사 케이티앤지생명과학 2015-07-09 WO disclosed
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 CYP2C9 692/4885CYP1A2 487/4885CYP2C19 887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.