Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDXK | O00764 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25302330 | 0.81 | KCNJ1 (0.33) | GRM4PDK2PDK4 | |
| SCHEMBL27223306 | 0.76 | PDXK (0.43) | PDXK | |
| SCHEMBL19308504 | 0.71 | PDE10A (0.32) | PDXK | |
| SCHEMBL29890134 | 0.70 | — | — | |
| SCHEMBL7251854 | 0.70 | — | — | |
| SCHEMBL12440989 | 0.70 | — | — | |
| SCHEMBL22445332 | 0.70 | CCR1 (0.42) | — | |
| SCHEMBL18597002 | 0.69 | PDE10A (0.31) | — | |
| SCHEMBL27223913 | 0.68 | PDXK (0.38) | PDXK | |
| SCHEMBL13328683 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545058-B1 | TETRAZOLO[1,5-a]PYRAZINE COMPOUNDS AS INHIBITORS OF HISTAMINE RECEPTORS | KALYPSYS INC (US) | 2016-08-24 | — | — | EP | disclosed |