Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17835716 | 0.84 | SMPD1 (0.62) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL3245222 | 0.84 | SMPD1 (0.67) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL18031233 | 0.82 | SMN1; SMN2 (0.60) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL18054821 | 0.81 | CA12 (0.47) | SMPD1HDAC6SMN1; SMN2HPGDRAB9A | |
| SCHEMBL18033077 | 0.81 | MAPT (0.38) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| Bicarbonate SCHEMBL5504807 | 0.80 | SMPD1 (0.62) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| Bicarbonate SCHEMBL5504809 | 0.80 | SMPD1 (0.62) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL2803357 | 0.80 | SMPD1 (0.54) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL1665370 | 0.80 | S1PR4 (0.47) | SMN1; SMN2HPGDNPC1RAB9AMAPT | |
| SCHEMBL26814603 | 0.80 | CYP1A2 (0.44) | HDAC1SMN1; SMN2HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10358453-B2 | Antiviral compounds | ALIOS BIOPHARMA, INC. (US) | 2019-07-23 | — | — | US | disclosed |
| WO-2016138158-A1 | ANTIVIRAL COMPOUNDS | ALIOS BIOPHARMA, INC. (US) | 2016-09-01 | — | — | WO | disclosed |
| US-20160244460-A1 | ANTIVIRAL COMPOUNDS | Janssen Pharmaceuticals, Inc. | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10358453-B2 | Antiviral compounds | MAVS, SARS1, ZC3HAV1 | SMPD1 69/4885HDAC1 684/4885HDAC8 629/4885 |
| US-20160244460-A1 | ANTIVIRAL COMPOUNDS | MAVS, SARS1, ZC3HAV1 | SMPD1 69/4885HDAC1 684/4885HDAC8 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.