Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | NOS1 | P29475 | 9/20 | 0.40 |
| ▸ | NOS2 | P35228 | 9/20 | 0.40 |
| ▸ | NOS3 | P29474 | 6/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006789 | 0.81 | CYP2C9 (0.43) | HRH3NOS1 | |
| SCHEMBL18033674 | 0.81 | TAAR1 (0.41) | TAAR1HRH3NOS1NOS2NOS3 | |
| SCHEMBL3677267 | 0.74 | MEN1 (0.34) | — | |
| SCHEMBL18006755 | 0.71 | HPGD (0.37) | — | |
| SCHEMBL28071130 | 0.71 | TAAR1 (0.59) | TAAR1HRH3 | |
| SCHEMBL25488430 | 0.70 | ESR1 (0.36) | — | |
| SCHEMBL25833598 | 0.69 | TAAR1 (0.61) | TAAR1HRH3 | |
| SCHEMBL8583 | 0.69 | CES2 (0.44) | — | |
| SCHEMBL29204036 | 0.69 | TAAR1 (0.55) | TAAR1HRH3 | |
| SCHEMBL18006682 | 0.69 | TAAR1 (0.46) | TAAR1HRH3NOS1NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016132134-A1 | THIAZOLE DERIVATIVES FOR THE TREATMENT OF ANIMAL TRYPANOSOMIASIS | UNIVERSITY OF DUNDEE (GB) | 2016-08-25 | — | — | WO | disclosed |