⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20552679 | 0.75 | — | — | |
| SCHEMBL434703 | 0.75 | — | — | |
| SCHEMBL1333515 | 0.75 | — | — | |
| SCHEMBL508447 | 0.75 | — | — | |
| SCHEMBL715205 | 0.72 | — | — | |
| SCHEMBL40927 | 0.72 | — | — | |
| Isobutane SCHEMBL30260038 | 0.72 | — | — | |
| SCHEMBL5555 | 0.72 | — | — | |
| Iodoform SCHEMBL2755155 | 0.72 | — | — | |
| SCHEMBL2755344 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296295-A1 | COMPOSITIONS AND METHODS FOR TREATING BETA-AMYLOID RELATED DISEASES | American Life Science Pharmaceuticals, Inc. (US) | 2018-03-21 | — | — | EP | disclosed |
| EP-2921486-B1 | Compositions and methods for treating beta-amyloid related diseases | AMERICAN LIFE SCIENCE PHARMACEUTICALS INC (US) | 2017-09-27 | — | — | EP | disclosed |
| US-20170008918-A1 | NOVEL CYP-EICOSANOID DERIVATIVES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-01-12 | — | — | US | disclosed |
| EP-2921486-A1 | Compositions and methods for treating beta-amyloid related diseases | American Life Science Pharmaceuticals, Inc. (US) | 2015-09-23 | — | — | EP | disclosed |
| EP-2462131-B1 | COMPOSITIONS AND METHODS FOR TREATING BETA-AMYLOID RELATED DISEASES | AMERICAN LIFE SCIENCE PHARMACEUTICALS INC (US) | 2014-10-15 | — | — | EP | disclosed |
| US-20110105603-A1 | COMPOSITIONS AND METHODS FOR TREATING BETA-AMYLOID RELATED DISEASES | AMERICAN LIFE SCIENCE PHARMACEUTICALS, INC. (US) | 2011-05-05 | — | — | US | disclosed |
| US-20090062561-A1 | DEUTERIUM-ENRICHED LATANOPROST | PROTIA, LLC (US) | 2009-03-05 | — | — | US | disclosed |