⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803530 | 0.75 | — | — | |
| SCHEMBL30507223 | 0.67 | — | — | |
| SCHEMBL13916787 | 0.67 | — | — | |
| SCHEMBL12691708 | 0.64 | — | — | |
| SCHEMBL508929 | 0.64 | — | — | |
| Iodomethane SCHEMBL799995 | 0.61 | — | — | |
| Iodoform SCHEMBL2755155 | 0.61 | — | — | |
| Iodomethane SCHEMBL87147 | 0.61 | — | — | |
| Iodomethane SCHEMBL118500 | 0.61 | — | — | |
| Iodomethane SCHEMBL10316995 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260042750-A1 | HETEROARYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF | DECIPHERA PHARMACEUTICALS LLC (US) | 2026-02-12 | — | — | US | disclosed |
| EP-4688792-A1 | KRAS INHIBITORS | Eli Lilly and Company (US) | 2026-02-11 | — | — | EP | disclosed |
| US-12479833-B2 | Heteroarylaminopyrimidine amide autophagy inhibitors and methods of use thereof | DECIPHERA PHARMACEUTICALS, LLC (US) | 2025-11-25 | — | — | US | disclosed |
| EP-4593811-A2 | DEUTERATED HINOKITIOL DERIVATIVES | The Board of Trustees of the University of Illinois (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2025129135-A2 | COMPOSITIONS COMPRISING USP1 INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025076235-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-04-10 | — | — | WO | disclosed |
| EP-3603674-B1 | COMBINATION OF MORPHINAN COMPOUNDS AND ANTIDEPRESSANT FOR THE TREATMENT OF INTRACTABLE AND CHRONIC PAIN | SUN PHARMACEUTICAL IND INC (US) | 2025-02-26 | — | — | EP | disclosed |
| US-20240368193-A1 | KRAS INHIBITORS | ELI LILLY AND COMPANY | 2024-11-07 | — | — | US | disclosed |
| WO-2024206766-A1 | KRAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2024-10-03 | — | — | WO | disclosed |
| WO-2024073125-A2 | DEUTERATED HINOKITIOL DERIVATIVES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-04-04 | — | — | WO | disclosed |
| EP-2418211-A1 | Deuterated morphinane compounds | Concert Pharmaceuticals Inc. (US) | 2012-02-15 | — | — | EP | disclosed |
| US-20120029007-A1 | MORPHINAN COMPOUNDS | CONCERT PHARMACEUTICALS INC. | 2012-02-02 | — | — | US | disclosed |
| EP-2397158-A2 | Combination of morphinan compounds and antidepressant for the treatment of pseudobulbar affect | CONCERT PHARMACEUTICALS, INC. (US) | 2011-12-21 | — | — | EP | disclosed |
| US-20110257214-A1 | MORPHINAN COMPOUNDS | SUN PHARMACEUTICAL INDUSTRIES, INC. | 2011-10-20 | — | — | US | disclosed |
| EP-2365808-A1 | COMBINATION OF MORPHINAN COMPOUNDS AND ANTIDEPRESSANT FOR THE TREATMENT OF PSEUDOBULBAR AFFECT, NEUROLOGICAL DISEASES, INTRACTABLE AND CHRONIC PAIN AND BRAIN INJURY | Concert Pharmaceuticals Inc. (US) | 2011-09-21 | — | — | EP | disclosed |
| EP-2334678-A1 | MORPHINAN COMPOUNDS | Concert Pharmaceuticals Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010062692-A1 | COMBINATION OF MORPHINAN COMPOUNDS AND ANTIDEPRESSANT FOR THE TREATMENT OF PSEUDOBULBAR AFFECT, NEUROLOGICAL DISEASES, INTRACTABLE AND CHRONIC PAIN AND BRAIN INJURY | CONCERT PHARMACEUTICALS INC. (US) | 2010-06-03 | — | — | WO | disclosed |
| WO-2010033801-A1 | MORPHINAN COMPOUNDS | CONCERT PHARMACEUTICALS INC. (US) | 2010-03-25 | — | — | WO | disclosed |
| US-20090062561-A1 | DEUTERIUM-ENRICHED LATANOPROST | PROTIA, LLC (US) | 2009-03-05 | — | — | US | disclosed |
| US-20080171772-A1 | e.g. Methyl 1-Benzyl-6-methoxy-1H-indole-2-carboxylate; glaucoma, dry eye, angiogenesis, cardiovascular conditions and diseases, wound healing, platelet aggregation and thrombosis | ALLERGAN, INC. | 2008-07-17 | — | — | US | disclosed |