Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | ACR | P10323 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547782 | 0.78 | KMT2A (0.36) | MAPTTDP1L3MBTL1POLBNR1H4 | |
| SCHEMBL548335 | 0.78 | MAPT (0.50) | MAPTTDP1L3MBTL1NR1H4MEN1 | |
| SCHEMBL18802919 | 0.77 | MAPT (0.49) | MAPTTDP1L3MBTL1NR1H4MEN1 | |
| SCHEMBL548289 | 0.75 | MAPT (0.42) | MAPTTDP1L3MBTL1POLBNR1H4 | |
| SCHEMBL548333 | 0.74 | ESR1 (0.47) | MAPTTDP1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL978333 | 0.73 | CES2 (0.35) | CES2TDP1 | |
| SCHEMBL547102 | 0.73 | TDP1 (0.61) | MAPTTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL548397 | 0.72 | MAPT (0.44) | MAPTNPSR1TDP1L3MBTL1POLB | |
| SCHEMBL548764 | 0.72 | ATM (0.41) | MAPTTDP1L3MBTL1POLBNR1H4 | |
| SCHEMBL547575 | 0.71 | MAPT (0.54) | MAPTNPSR1TDP1L3MBTL1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739485-B1 | RESIST COMPOSITION | MITSUBISHI GAS CHEMICAL CO (JP) | 2016-08-31 | — | — | EP | disclosed |